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N-phenyliminodiacetic acid as an etchant/primer for dentin bonding
G E Schumacher1, J M Antonucci, P S Bennett
1Clinical Center/CODC, National Institutes of Health, Bethesda, Maryland 20892.
Journal of Dental Research
|January 1, 1997
Summary
N-phenyliminodiacetic acid simplifies dentin bonding by acting as both an etchant and primer. When used in an acetone:water solution without prior nitric acid etching, it achieves strong composite-to-dentin adhesion comparable to traditional methods.
Area of Science:
- Dental Materials Science
- Adhesive Dentistry
- Polymer Chemistry
Background:
- Effective composite-to-dentin bonding is crucial for durable dental restorations.
- Current methods often involve multi-step protocols using nitric acid (HNO3) pre-treatment and specific primers like N-phenylglycine.
- Surface-initiated polymerization plays a key role in achieving strong adhesion.
Purpose of the Study:
- To evaluate N-phenyliminodiacetic acid as a dual-function etchant and primer for dentin bonding.
- To simplify the dentin bonding procedure by potentially eliminating the need for nitric acid pre-treatment.
- To compare the tensile bond strength (TBS) of novel two-step protocols with a standard three-step control.
Main Methods:
- A randomized 2(3) factorial design investigated the effects of conditioner (HNO3 vs. none), primer (N-phenylglycine vs. N-phenyliminodiacetic acid), and solvent (acetone vs. acetone:H2O).
- Tensile bond strength (TBS) was measured after 24-hour water storage.
- Statistical analysis included ANOVA and Duncan's Multiple Range test.
Main Results:
- Primer solvent was critical when HNO3 was omitted; N-phenyliminodiacetic acid in acetone alone yielded low TBS.
- N-phenyliminodiacetic acid in an acetone:H2O mixture, without prior HNO3 etching, produced TBS comparable to the control group.
- The control group utilized HNO3, N-phenylglycine in acetone, and p-PMDM in acetone.
Conclusions:
- N-phenyliminodiacetic acid effectively functions as both an etchant and a primer, simplifying the bonding technique.
- The combination of N-phenyliminodiacetic acid in an acetone:H2O solvent provides a simplified, effective method for achieving strong dentin adhesion.
- This dual-action approach offers a promising alternative for PMDM-mediated adhesion to dentin.