[The dynamics of bone defect healing after the implantation of collagen and hydroxyapatite complexes (an experimental...

Healing of standard bone defects in the distal third of the femoral bone was studied in experiments on 48 rats. In order to repair the defect, colapol or a new composition with structurized collagen and hydroxyapatite powder and granulate KP-2 were used. Histological study showed that healing was optimal after repair with KP-2 composition: callus formed rapidly, as did the typical osseogranular complexes. Newly formed bone structures mature much sooner than after implantation of colapol. The authors come to a conclusion that the use of KP-2 composition holds good promise as material for maxillofacial surgery in plastic repair of bone defects.