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Severe allergy to sorbolene cream
A R MacKenzie-Wood1, S Freeman
1Skin and Cancer Foundation Australia, Darlinghurst, New South Wales, Australia.
The Australasian Journal of Dermatology
|February 1, 1997
Summary
A patient developed allergic contact dermatitis to chlorocresol, a preservative in sorbolene cream, after years of occupational exposure. Delayed diagnosis highlights the importance of thorough patch testing for persistent dermatitis.
Area of Science:
- Dermatology
- Allergology
- Occupational Health
Background:
- Occupational hand and foot dermatitis can significantly impact a patient's quality of life and career.
- Barrier creams are often used in occupational settings to prevent skin irritation.
Observation:
- A 40-year-old motor mechanic developed persistent hand and foot dermatitis while using sorbolene cream.
- The patient was unable to continue his trade due to the severity of his dermatitis.
Findings:
- A diagnosis of allergic contact dermatitis to chlorocresol was made 16 years after symptom onset.
- Chlorocresol, a common preservative in sorbolene and corticosteroid creams, was identified as the allergen.
- Initial patch testing in 1983 was negative, likely due to the omission of chlorocresol and sorbolene cream.
Implications:
- This case underscores the importance of considering delayed-type hypersensitivity reactions in chronic dermatitis.
- Thorough patch testing, including specific allergens and product vehicles, is crucial for accurate diagnosis.
- Occupational dermatitis management requires identification and avoidance of causative agents.