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Multiple hereditary osteochondromatosis. Two cases with ankle and knee deformities
A Glockenberg1, E Sobel, S J Levitz
1Department of Orthopedic Sciences, New York College of Podiatric Medicine, New York, USA.
Journal of the American Podiatric Medical Association
|February 1, 1997
Summary
Multiple hereditary osteochondromatosis, a common inherited bone disorder, often presents with ankle deformities. Clinicians must be aware of this condition due to its prevalence and potential for malignant transformation.
Area of Science:
- Orthopedics
- Genetics
- Oncology
Background:
- Multiple hereditary osteochondromatosis (MHO), also known as multiple hereditary exostoses, is the most prevalent inherited systemic bone disorder.
- It is characterized by the development of multiple benign bone tumors (osteochondromas).
Observation:
- This report details two case histories of MHO.
- Ankle deformity was observed in 50% of reported cases.
Findings:
- MHO is a common inherited systemic disorder of bone.
- The condition frequently involves the ankle and carries a risk of malignant transformation.
Implications:
- Familiarity with MHO is crucial for clinicians due to its frequency and associated complications.
- Early recognition and management are important for patients with MHO, particularly regarding ankle deformities and malignant potential.