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Addison disease in patients treated with glucocorticoid therapy
C C Cronin1, N Callaghan, P J Kearney
1Department of Medicine, Cork University Hospital, Ireland.
Archives of Internal Medicine
|February 24, 1997
Summary
Diagnosing acute adrenal crisis is challenging, especially when patients receive glucocorticoid treatment. This condition, primarily a mineralocorticoid deficiency, can be fatal if unrecognized, even with concurrent steroid therapy.
Area of Science:
- Endocrinology
- Internal Medicine
Background:
- Acute adrenal crisis is a life-threatening condition associated with unrecognized chronic adrenocortical failure.
- Diagnosis can be complicated by concurrent glucocorticoid therapy.
- Glucocorticoid medications like prednisone and prednisolone have limited mineralocorticoid activity.