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Updated: Aug 2, 2026

Imaging Cell Shape Change in Living Drosophila Embryos
Published on: March 30, 2011
misshapen encodes a protein kinase involved in cell shape control in Drosophila
J E Treisman1, N Ito, G M Rubin
1MCB and HHMI, University of California at Berkeley 94704, USA. treisman@saturn.med.nyu.edu
Abstract:
We have identified a novel protein kinase encoded by the misshapen gene, which is required for the normal shape and orientation of Drosophila photoreceptor cells. misshapen is also expressed in the embryonic mesoderm, pole plasm and other sites of cell shape change or movement. We propose that msn may act in a signal transduction pathway leading to cytoskeletal re-arrangements.
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