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Evaluation of predictive factors for multiple pregnancies during gonadotropin/IUI treatment
J M Goldfarb1, B Peskin, C Austin
1Department of Ob/Gyn, University Hospitals of Cleveland, Case Western Reserve University, Ohio 44106, USA.
Purpose:
Our purpose was to analyze factors for their predictability of multiple pregnancies in patients treated with a combination of human menopausal gonadotropins (hMG) and intrauterine insemination (IUI).
Methods:
The records of all patients conceiving through treatment with hMG/IUI were reviewed for factors predictive of multiple pregnancy.
Results:
Ninety-one pregnancies reviewed included 78 singleton (86%), 8 twin (9%), and 5 higher-order pregnancies (5%). The total number of follicles > 10 mm was greater in the multiple-pregnancy group and there was a decreased number of postwash sperm in the multiple-pregnancy group. Otherwise there was no significant difference in the factors analyzed.
Conclusions:
No factor or combination of factors predicts multiple pregnancies to a degree that it would be helpful in managing or counseling patients.