Basopenia as an indicator of ovulation (a short term clinical study)

In the present study 60 cases age ranging from 18-40 years were studied for variation in the absolute basophil count on the different days of menstrual cycle. At the time of ovulation a statistically significant decrease in the number of basophil count was noted. The decrease in the number of basophil at mid cycle coincided with the irregular follicle seen by sonography, which indicated ovulation. The basophil count then increased during the luteal phase. Basopenia at the time of ovulation was probably due to migration of these cells from the peripheral blood towards the rupturing follicle for the release of histamine required for ovulation.