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Effect of beta-endorphin on striatal dopamine metabolism
Research Communications in Chemical Pathology and Pharmacology
|September 1, 1977
Abstract:
Acute intraventricular administration of human beta-endorphin increased 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) concentrations in rat striatum at a time when the catatonic effect was also present. This effect of beta-endorphin is compatible with increased striatal dopamine turnover and is similar to the effect noted previously with morphine administration.