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Related Experiment Videos

Deep venous thrombosis in Taiwan

H C Lee1, W B Liao, M J Bullard

  • 1Emergency Department Section of First Cardiology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.

Japanese Heart Journal
|November 1, 1996
PubMed
Summary

Deep venous thrombosis (DVT) is more common in the left leg, but right leg DVTs are more likely to cause pulmonary embolism. A significant association exists between cancer and DVT, warranting investigation for malignancy in unexplained cases.

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Area of Science:

  • Vascular Medicine
  • Oncology
  • Epidemiology

Background:

  • Deep venous thrombosis (DVT) is a significant clinical concern.
  • Cancer is a known risk factor for DVT.
  • Understanding the laterality of DVT and its association with pulmonary embolism is crucial.

Purpose of the Study:

  • To analyze the laterality of deep venous thrombosis (DVT) in relation to pulmonary embolism.
  • To investigate the prevalence of cancer in patients diagnosed with DVT.
  • To explore the relationship between DVT, cancer, and pulmonary embolism.

Main Methods:

  • Retrospective review of 245 patients diagnosed with DVT between 1989 and 1995.
  • Analysis of patient demographics, affected leg, and occurrence of pulmonary embolism.

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  • Assessment of cancer diagnosis and primary site in relation to DVT.

    • Main Results:

    • The left leg showed a higher incidence of DVT (2.4:1 ratio).
    • The right leg DVT was associated with a higher risk of acute pulmonary embolism (3.0:1 ratio).
    • Cancer was present in 16.3% of patients, with gastrointestinal (GI) adenocarcinoma being the most common malignancy.

    Conclusions:

    • Left leg DVT is more frequent, but right leg DVT carries a higher risk of pulmonary embolism.
    • A strong correlation between cancer and DVT necessitates screening for underlying malignancy in unexplained DVT cases.
    • Early detection and management of DVT, considering laterality and associated risks, are vital.