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Endocarditis caused by Pasteurella multocida

V Lehmann, S B Knutsen, E Ragnhildstveit

    Scandinavian Journal of Infectious Diseases
    |January 1, 1977
    PubMed
    Summary
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    Pasteurella multocida can cause subacute bacterial endocarditis, a serious heart valve infection. Prompt diagnosis and prolonged antibiotic treatment, along with valve surgery, are crucial for recovery.

    Area of Science:

    • Infectious Diseases
    • Cardiology
    • Microbiology

    Background:

    • Subacute bacterial endocarditis (SBE) typically presents with non-specific symptoms.
    • Identifying the causative pathogen is crucial for effective treatment and patient outcomes.

    Observation:

    • A previously healthy 51-year-old man presented with symptoms of endocarditis, including low-grade fever, aortic insufficiency, and arterial emboli.
    • Blood cultures consistently isolated an atypical strain of Pasteurella multocida.

    Findings:

    • Protracted treatment with high-dose penicillin G was required to eradicate the Pasteurella multocida infection.
    • Surgical intervention, involving aortic valve resection and prosthesis implantation, was necessary for the patient's recovery.

    Implications:

    Related Experiment Videos

    • This case highlights Pasteurella multocida as a potential cause of subacute bacterial endocarditis, even in immunocompetent individuals.
    • Clinicians should consider Pasteurella multocida in the differential diagnosis of SBE, particularly with atypical presentations.
    • Aggressive and prolonged antimicrobial therapy, combined with surgical management when indicated, is essential for successful treatment of P. multocida endocarditis.