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Primary ovarian carcinoid tumor

Y Y Chou¹, C T Shun, S C Huang

¹Department of Pathology, National Taiwan University Hospital, Taipei.

Journal of the Formosan Medical Association = Taiwan Yi Zhi

|February 1, 1996

Summary

Pure primary ovarian carcinoid tumors are rare, with only 21 cases documented. This report details a unique case in a young woman, highlighting diagnostic markers and successful surgical management.

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Area of Science:

Gynecologic Oncology
Pathology
Endocrinology

Background:

Pure primary ovarian carcinoid tumors are exceptionally rare, posing diagnostic challenges.
Limited literature exists on these neoplasms, with only 21 cases previously reported.

Observation:

A case of a pure primary ovarian carcinoid tumor in a 25-year-old woman with no carcinoid syndrome is presented.
The tumor, devoid of teratomatous elements, exhibited uniform cells in nests or trabecular patterns on light microscopy.
Immunohistochemical staining (argyrophilic, chromogranin) and ultrastructural analysis confirmed neurosecretory granules.

Findings:

The differential diagnosis included granulosa cell tumor, necessitating advanced diagnostic techniques.
Confirmed diagnosis via specific staining and ultrastructural morphology.
Patient underwent successful left oophorectomy with an uneventful postoperative recovery.

Implications:

This case expands the understanding of rare ovarian neoplasms.
Highlights the importance of immunohistochemistry and electron microscopy in diagnosing ovarian carcinoid tumors.
Contributes to the limited literature on the pathology, diagnosis, and management of primary ovarian carcinoid tumors.

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