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Lyme disease during pregnancy

¹Department of Maternal-Fetal Medicine, Women & Infants Hospital of Rhode Island, Providence, USA.

Infectious Disease Clinics of North America

|March 1, 1997

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Lyme disease during pregnancy is not typically harmful to the fetus. Recent studies show that Borrelia burgdorferi infection does not pose a significant risk for fetal complications.

Area of Science:

Infectious Diseases
Obstetrics & Gynecology
Pediatrics

Background:

Lyme disease, caused by Borrelia burgdorferi, shares similarities with syphilis.
Past concerns existed regarding fetal infection and teratogenicity from maternal Lyme disease.

Purpose of the Study:

To review current evidence on the fetal safety of Lyme disease during pregnancy.
To address past concerns about Borrelia burgdorferi's impact on fetal development.

Main Methods:

Review of retrospective case reports.
Analysis of recent prospective study data.

Main Results:

Initial retrospective reports suggested potential risks.
More recent prospective data indicate a reassuring, benign outcome for the fetus.

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Conclusions:

Current evidence supports the benign nature of Lyme disease in pregnancy regarding fetal health.
Prospective data have alleviated concerns about Borrelia burgdorferi teratogenicity.