Site-specific integration by adeno-associated virus: a basis for a potential gene therapy vector

Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors.

Gene therapy·2010

Characterization of a bipartite recombinant adeno-associated viral vector for site-specific integration.

Human gene therapy·2007

Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system.

Journal of virology·2001

Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors.

Gene therapy·2001

Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences.

Journal of virology·2001

Recombinant angiostatin prevents retinal neovascularization in a murine proliferative retinopathy model.

Gene therapy·2001

An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production.

Gene therapy·2026

A gene therapy approach to prevent dilated intercellular space, a hallmark of gastroesophageal reflux disease.

Gene therapy·2026

Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.

Gene therapy·2026

Bone- and muscle-targeted adeno-associated viral vectors enable tissue-selective vitamin D receptor knockdown in mice.

Gene therapy·2026

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

Gene therapy·2026

rAAV production cost analysis: Indication-specific cost per dose and reduction strategies.

Gene therapy·2026

Spatial Transcriptomics-Inspired Targeted Hydrogel for Dental Pulp Therapy via Strengthen Macrophage Communication.

Advanced healthcare materials·2026

Trans-interface coupling in the tetrameric enzyme underlies allosteric control in Escherichia coli biosynthetic threonine deaminase.

Journal of structural biology: X·2026

Tissue integration in the CAM assay, collagen intensity and near-interface cell density data for novel emulsion electrospun DegraPol®-Bakuchiol fiber meshes that were characterized by FTIR and for fiber thickness and pore size.

Data in brief·2026

Topical Recombinant Human Type III Collagen for Atopic Dermatitis: Evaluation of Efficacy and Safety.

European journal of pharmacology·2026

Poly(2-methoxyethyl acrylate) analog coatings enhance long-term endothelialization and support blood-compatible healing of vascular grafts in nonhuman primate models.

Biomaterials advances·2026

Intermittent fasting promotes remodeling of neural and vascular networks in visceral white adipose tissue.

iScience·2026

Related Experiment Videos

Site-specific integration by adeno-associated virus: a basis for a potential gene therapy vector

Related Concept Videos

Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors.

Characterization of a bipartite recombinant adeno-associated viral vector for site-specific integration.

Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system.

Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors.

Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences.

Recombinant angiostatin prevents retinal neovascularization in a murine proliferative retinopathy model.

An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production.

A gene therapy approach to prevent dilated intercellular space, a hallmark of gastroesophageal reflux disease.

Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.

Bone- and muscle-targeted adeno-associated viral vectors enable tissue-selective vitamin D receptor knockdown in mice.

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

rAAV production cost analysis: Indication-specific cost per dose and reduction strategies.

Spatial Transcriptomics-Inspired Targeted Hydrogel for Dental Pulp Therapy via Strengthen Macrophage Communication.

Trans-interface coupling in the tetrameric enzyme underlies allosteric control in Escherichia coli biosynthetic threonine deaminase.

Tissue integration in the CAM assay, collagen intensity and near-interface cell density data for novel emulsion electrospun DegraPol®-Bakuchiol fiber meshes that were characterized by FTIR and for fiber thickness and pore size.

Topical Recombinant Human Type III Collagen for Atopic Dermatitis: Evaluation of Efficacy and Safety.

Poly(2-methoxyethyl acrylate) analog coatings enhance long-term endothelialization and support blood-compatible healing of vascular grafts in nonhuman primate models.

Intermittent fasting promotes remodeling of neural and vascular networks in visceral white adipose tissue.

Related Experiment Videos

Site-specific integration by adeno-associated virus: a basis for a potential gene therapy vector

Related Concept Videos

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