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The mydriatic effect of tropicamide and its diagnostic use in Alzheimer's disease
A Reitner1, I Baumgartner, C Thuile
1Department of Ophthalmology, University of Vienna, Austria. andreas.Reitner@akh-wien.ac.at
Vision Research
|January 1, 1997
Abstract:
The mydriatic effect of topically administered tropicamide was investigated as a possible diagnostic indicator for Alzheimer's disease. Although an initial series seemed to show a correlation between hypersensitivity to tropicamide and intellectual impairment, subsequent testing showed a greater inter- and intra-individual variation than that between the normal group and the group of patients with intellectual impairment. This procedure seems, therefore, to lack sufficient specificity to be useful for such a diagnostic purpose.