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Updated: Aug 2, 2026

Whole Mount Labeling of Cilia in the Main Olfactory System of Mice
Published on: December 27, 2014
Inositol 1,4,5-trisphosphate receptor expression in mammalian olfactory tissue
G Smutzer1, J E Zimmerman, C G Hahn
1Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA. smutzerg@mail.med.upenn.edu
Abstract:
Two cDNAs encoding inositol 1,4,5-trisphosphate (IP3) receptors were amplified from rat olfactory tissue, and both exhibited 100% sequence identity to the short (Segment II - ) variant of type I IP3 receptor. Type III IP3 receptor was also expressed in olfactory tissue. The distribution of IP3 receptors included the olfactory epithelium, lamina propria, and glandular tissue. These results demonstrate the co-expression of multiple IP3 receptor subtypes in olfactory cells, and suggest multiple functions for IP3 receptors in this tissue.
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