Combined Laparoscopic Cryosurgery in the Treatment of Polycystic Ovarian Disease

This paper presents the results of treating 32 infertile women afflicted with polycystic ovarian disease by combined laparoscopic cryosurgery. Each of these patients had been resistant to the induction of ovulation with clomiphene. Cryosurgery was performed under laparoscopic control with a special cryosurgical probe. Prior to freezing, we did a biopsy of each patient's ovaries and, in 13 cases, enucleation of the cyst. In 6 to 14 months after surgery, normalization of the menstrual cycle occurred in 24 women. The level of steroid hormones, which were studied in the first and second parts of the menstrual cycle before and after surgery, rose to normal (P<0.05; P<0.01). Of the total number of women, 5 had conceived after 3 months, 12 after 6 months, and 3 after 14 months. We conclude that combined laparoscopic cryosurgery is an effective method of treatment for polycystic ovarian disease.