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Early infantile epileptic encephalopathy: report of one case
1Department of Pediatrics, Chang Gung Children's Hospital, Kaohsiung, Taiwan, R.O.C.
Insights
This case report details a male infant with daily tonic seizures and diarrhea, diagnosed with early infantile epileptic encephalopathy. The condition, marked by burst-suppression EEG and corpus callosum hypoplasia, has a poor prognosis.
Area of Science:
- Pediatric Neurology
- Epileptology
- Neuroimaging
Background:
- Early infantile epileptic encephalopathy (EIEE) is a severe epilepsy syndrome.
- It presents with intractable seizures and developmental regression in the first year of life.
- Diagnostic challenges include differentiating EIEE from other early-onset seizure disorders.
Abstract:
A 47-day-old male infant had daily tonic seizures and diarrhea since 7 days of age. The seizures occurred several times a day and were characterized by tonic spasms of limbs and an abnormal gaze. Interictal electroencephalography (EEG) showed a burst-suppression pattern. Brain magnetic resonance imaging revealed hypoplasia of corpus callosum. Early infantile epileptic encephalopathy was diagnosed based on the clinical and EEG features. The author here reports on this patient focusing on the diagnosis and dismal prognosis.