[Ultrastructural changes in the liver in experimental diffuse peritonitis]

Ultrastructural changes in the liver were studied on the 1st, 2nd, 4th and 8th days of the disease in random-bred dogs with induced diffuse microbial peritonitis. As early as on the 1st day of the disease considerable changes of hepatocytes, hepatic stroma, microcirculatory and bile tracts were detected. Dystrophic and necrobiotic changes in hepatic cells were most marked at 4-8 days of the disease. By the end of the 2nd day the edema of the hepatic stroma subsided, but subsequently it increased markedly. In microcirculatory tracts of the liver and greatest changes were found at 4-8 days in lymphatic capillaries, up to their complete blocking.