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Fermentation monitoring and process control
1Institut fur Technische Chemie Universitat Hannover Callinstrasse 3, 30167, Hannover, Germany
Current Opinion in Biotechnology
|April 1, 1997
Summary
Modern analytical online methods, like 2D fluorescence, offer new insights into bioprocesses. This data aids in understanding biotransformations and developing control strategies for improved productivity and cost reduction.
Area of Science:
- Biotechnology
- Analytical Chemistry
- Process Engineering
Background:
- Bioprocesses require advanced monitoring for optimization.
- Traditional methods may lack the resolution for complex biotransformations.
Purpose of the Study:
- To highlight the utility of modern analytical online methods in bioprocess analysis.
- To demonstrate the benefits of two-dimensional fluorescence measurements for bioprocess understanding and control.
Main Methods:
- Utilizing two-dimensional fluorescence measurements as a modern analytical online method.
- Applying data analysis to interpret bioprocess insights.
Main Results:
- Gained new insights into complex bioprocesses.
- Enabled better documentation and understanding of biotransformations.
- Facilitated the development of efficient control strategies.
Conclusions:
- Two-dimensional fluorescence measurements provide valuable data for bioprocesses.
- Enhanced understanding leads to improved process control, productivity, and cost-efficiency.
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