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Gender differences in cortical glucose metabolism in Alzheimer's disease and normal aging
B V Siegel1, L Shihabuddin, M S Buchsbaum
1Department of Psychiatry, University of California, Irvine, USA.
The Journal of Neuropsychiatry and Clinical Neurosciences
|January 1, 1996
Abstract:
Male Alzheimer's disease patients, studied with 18-fluoro-2-deoxyglucose positron emission tomography while performing a verbal memory test, showed a right-greater-than-left asymmetry of cortical metabolism that tended to be greater than that in healthy, age-matched control subjects. This asymmetry was absent in female patients, preliminarily suggesting a propensity for left hemispheric involvement in the Alzheimer's disease process in males.