Related Experiment Video
Updated: Jul 15, 2026
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
[Use of coronary vessel prosthesis. Complex coronary angioplasty under general anesthesia]
L J Szatmáry1, G Nyikos, G Kerkovits
1Semmelweis Orvostudományi Egyetem, Er- és Szívsebészeti Klinika, Budapest.
Insights
Percutaneous transluminal coronary angioplasty (PTCA) with stenting effectively treated ischemic patients, showing good results without complications. This promising technique optimizes PTCA outcomes for better cardiac care.
Area of Science:
- Interventional Cardiology
- Vascular Medicine
Context:
- Percutaneous transluminal coronary angioplasty (PTCA) is a common procedure for treating ischemic heart disease.
- The integration of coronary stenting aims to improve immediate and long-term outcomes of PTCA.
- Patient selection and procedural management are critical for success in high-risk individuals.
Purpose:
- To evaluate the efficacy and safety of coronary stenting as an adjunct to PTCA in ischemic patients.
- To assess the incidence of complications, including myocardial infarction, emergency surgery, death, and thrombosis.
- To investigate the management of in-stent restenosis following initial stenting.
Summary:
- A total of 437 ischemic patients underwent PTCA, with 29 (6.6%) receiving 34 stents. Emergency, semi-elective, and elective stenting were performed.
- Angiological success was achieved with no myocardial infarction, emergency surgery, or death. One-month follow-up with aspirin and ticlopidine showed no intracoronary thrombosis.
- High-risk patients treated under general anesthesia experienced no procedural complications. In-stent restenosis (17%) was managed by redilation.
Impact:
- Coronary stenting following PTCA demonstrates a promising approach for optimizing treatment results in ischemic heart disease.
- The findings support the routine application of stenting worldwide to enhance patient outcomes.
- Establishing well-funded interventional cardiology centers is crucial for the widespread adoption of this technique.
Abstract:
In 1995 we attempted to treat with PTCA 437 ischemic patients. We stended 29 patients (6.6%) with 34 stents. Emergency stenting was done in 5, semi-elective stenting in 6, and elective stents were applied in 18 patients with restenosis. We have achieved good angiological results without occurrence of myocardial infarction, with no emergency open heart surgery or death. No intracoronary thrombosis was observed during one-month follow-up with combined aspirin and ticlopidin treatment. Hemodynamical and angiological high-risk patients were treated under general anesthesia with assisted respiration. No complications were observed during the procedures. In cases of in-stent restenosis (17%) we redilated the coronary artery. This technique proved to be promising and is routinely applied world-wide to optimise immediate and long-term results of PTCA. The realisation of such interventional cardiological centers with appropriate financial background is an absolute requirement for spreading this technique in Hungary.
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