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The relation between induced abortion and ectopic pregnancy

H K Atrash1, L T Strauss, J S Kendrick

  • 1Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Obstetrics and Gynecology
|April 1, 1997
PubMed
Summary

A history of induced abortion does not appear to increase a woman's risk of ectopic pregnancy. This case-control study found no evidence linking prior induced abortions to a higher risk of ectopic pregnancy.

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Area of Science:

  • Reproductive Health
  • Obstetrics & Gynecology
  • Epidemiology

Background:

  • Ectopic pregnancy is a significant cause of maternal morbidity.
  • The potential impact of induced abortion on subsequent ectopic pregnancy risk is a public health concern.

Purpose of the Study:

  • To investigate the association between a history of induced abortion and the risk of ectopic pregnancy.

Main Methods:

  • A case-control study was conducted involving women with ectopic pregnancy and controls.
  • Data were collected from a major metropolitan hospital in Georgia between October 1988 and August 1990.
  • Statistical analyses, including stratified analysis and logistic regression, were used to assess risk.

Main Results:

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  • The study included 182 cases and 1056 controls, predominantly non-Hispanic black women.
  • A history of induced abortion was reported by 34% of cases and 36% of controls.
  • The adjusted odds ratio for ectopic pregnancy associated with induced abortion history was 0.9 (95% CI 0.6, 1.3), indicating no increased risk.
  • Conclusions:

    • There is no evidence to suggest that one or more induced abortions increase a woman's risk of ectopic pregnancy.
    • Findings suggest that induced abortion history is not a significant risk factor for ectopic pregnancy.