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Related Experiment Videos

Time to pregnancy and preterm delivery

T B Henriksen1, D D Baird, J Olsen

  • 1Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark.

Obstetrics and Gynecology
|April 1, 1997
PubMed
Summary

Subfertile women face a higher risk of preterm delivery, with longer conception times increasing this risk. This holds true even without infertility treatments, highlighting a significant pregnancy complication for subfertile individuals.

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Area of Science:

  • Obstetrics and Gynecology
  • Reproductive Health
  • Perinatal Epidemiology

Background:

  • Subfertility is a growing concern affecting numerous couples worldwide.
  • Preterm delivery remains a leading cause of neonatal morbidity and mortality.
  • Understanding risk factors for preterm birth is crucial for improving pregnancy outcomes.

Purpose of the Study:

  • To investigate the association between subfertility and the risk of preterm delivery.
  • To determine if time to conception influences preterm birth rates.
  • To assess if infertility treatment status modifies this relationship.

Main Methods:

  • Analysis of data from two large, population-based Danish cohort studies (Aalborg-Odense and Aarhus).
  • Inclusion of approximately 20,000 deliveries, focusing on women with planned pregnancies.

Related Experiment Videos

  • Categorization of women based on time to pregnancy (≤6 months, 7-12 months, >1 year) and infertility treatment status.

    • Main Results:

    • Women with a time to pregnancy of 7-12 months showed a 1.3-fold increased risk of preterm delivery.
    • A time to pregnancy exceeding 12 months was associated with a 1.6 to 1.7-fold increased risk of preterm delivery.
    • These associations persisted even after excluding women who underwent infertility treatment.

    Conclusions:

    • Subfertility and clinically defined infertility are linked to an increased likelihood of preterm delivery.
    • Longer delays in conception are associated with higher preterm birth risks.
    • The findings emphasize the need for closer monitoring of pregnancies in subfertile women, irrespective of treatment history.