Related Experiment Video
Updated: Jul 12, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
A histologic evaluation of localized ridge augmentation utilizing DFDBA in combination with e-PTFE membranes and
J M Doblin1, L M Salkin, J R Mellado
1Department of Periodontology, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140, USA.
Abstract:
This study evaluated histologically and clinically the use of decalcified freeze-dried bone allograft in conjunction with Gore-Tex Augmentation Material and Memfix bone pins for localized ridge augmentation in three cases. Biopsies taken at 3, 6, and 9 months were evaluated. It was concluded that: (1) guided bone regeneration may be performed at local immediate extraction sites when flap design permits primary wound closure; (2) decalcified freeze-dried bone allografts used in conjunction with supporting pins may contribute to successful bone regeneration either by osseoinduction or osseoconduction, and/or by maintaining the membrane-created space during the early events in wound healing; and (3) at 9 months, guided bone regeneration utilizing Gore-Tex Augmentation Material membranes and decalcified freeze-dried bone allografts resulted in the formation of dense, viable new bone.

