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Related Experiment Videos

Colorectal cancer. Clinical and pathologic features

R M Gore1

  • 1Department of Radiology, Evanston Hospital-McGaw Medical Center of Northwestern University, Illinois, USA.

Radiologic Clinics of North America
|March 1, 1997
PubMed
Summary

Colorectal cancer remains deadly despite advances, with no change in incidence or survival rates. Earlier detection of polyps and cancers, plus improved surgical and multimodal treatments, are crucial.

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Area of Science:

  • Oncology
  • Gastroenterology
  • Cancer Research

Background:

  • Colorectal cancer (CRC) pathogenesis understanding has improved.
  • Current treatments can alter the natural history for many average and high-risk patients.

Purpose of the Study:

  • Highlight the persistent challenge of colorectal cancer mortality.
  • Emphasize the need for advancements in early detection and treatment strategies.

Main Methods:

  • Review of current understanding of colorectal cancer pathogenesis.
  • Analysis of historical incidence and survival rates.
  • Evaluation of existing surgical and multimodality treatment approaches.

Main Results:

  • Despite improved understanding and treatment capabilities, colorectal cancer remains a leading cause of death.
  • There has been no significant change in colorectal cancer incidence or survival rates over the past four decades.
  • Current strategies are insufficient to overcome the disease's lethality.

Conclusions:

  • There is an ongoing, critical need for earlier detection of polyps and cancers.
  • Aggressive surgical intervention for primary tumors remains essential.
  • Improved multimodality treatment strategies are required for metastatic colorectal cancer.

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