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Human leptin has natriuretic activity in the rat

E K Jackson1, P Li

  • 1Department of Pharmacology, University of Pittsburgh Medical Center, Pennsylvania 15213-2582, USA.

The American Journal of Physiology
|March 1, 1997
PubMed
Summary

Human leptin (h-leptin) acts as a diuretic and natriuretic factor in rats, increasing urine volume and sodium excretion. This suggests a potential role for h-leptin in regulating kidney function.

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