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Updated: Oct 23, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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The management of ruptured intracranial aneurysm in sickle cell anemia. Case report

R A Close, W A Buchheit

    Journal of Neurosurgery
    |November 1, 1977
    PubMed

    The problems of sickle cell disease and its complications is discussed. Subarachnoid hemorrhage is not a common complication of sickle cell disease and should be evaluated in the same way as if it were not associated with the disease. Patients with sickle cell trait have an added risk during angiography and hypotensive anesthesia. Guidlines are given for angiography and craniotomy with hypotensive anesthesia and reduction of brain volume in these patients.

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