Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffusion imaging with a multi-echo MISSTEC sequence

F Franconi1, F Lethimonnier, C B Sonier

  • 1Unité INSERM U316, Faculté de Médecine, Tours, France.

Journal of Magnetic Resonance Imaging : JMRI
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Potential Source Apportionment and Meteorological Conditions Involved in Airborne <sup>131</sup>I Detections in January/February 2017 in Europe.

Environmental science & technology·2018
Same author

Genomic medicine France 2025.

Annals of oncology : official journal of the European Society for Medical Oncology·2018
Same author

Trace elements and Pb isotopes in soils and sediments impacted by uranium mining.

The Science of the total environment·2016
Same author

Mitochondria can orchestrate sex differences in cell fate of vascular smooth muscle cells from rats.

Biology of sex differences·2015
Same author

Uranium decay daughters from isolated mines: Accumulation and sources.

Journal of environmental radioactivity·2015
Same author

In vitro expansion of U87-MG human glioblastoma cells under hypoxic conditions affects glucose metabolism and subsequent in vivo growth.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine·2015
Same journal

Structural MRI Volumetry Index for Differentiation of Progressive Supranuclear Palsy From Parkinson's Disease and Multiple System Atrophy by Automatic Segmentation: A Comparison With Magnetic Resonance Parkinsonism Index.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Integrating nnU-Net Segmentation and Clinical-Radiomics for Multicenter MRI-Based Assessment of Soft Tissue Sarcoma Grade and Ki-67 Expression.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Optimization of Respiratory Training Methods for Cardiac Magnetic Resonance Imaging.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Editorial for "Voxel-Wise Radiomics Habitat Analysis of Post-Treatment Gliomas for Noninvasive Differentiation of True Progression and Pseudoprogression".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Demyelinating From Axonal Polyneuropathies.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Mapping Fatty Acid Composition in the Human Knee: Short-Term Repeatability at 3T.

Journal of magnetic resonance imaging : JMRI·2026
See all related articles

A new imaging method, MISSTEC, accurately measures water-diffusion coefficients using simultaneous spin and stimulated echoes. This technique halves acquisition time compared to the standard IntraVoxel Incoherent Motion (IVIM) method, showing excellent agreement in results.

Area of Science:

  • Medical Imaging
  • Diffusion MRI
  • Biophysics

Background:

  • Accurate measurement of the water-diffusion coefficient is crucial in various biological and medical applications.
  • Conventional diffusion imaging methods, such as the IntraVoxel Incoherent Motion (IVIM) method, can be time-consuming.

Purpose of the Study:

  • To introduce and validate a novel imaging sequence, MISSTEC (Multi-echo Incoherent Stimulated Echo acquisition), for efficient water-diffusion coefficient measurement.
  • To assess the accuracy and speed of the MISSTEC sequence compared to established methods.

Main Methods:

  • The MISSTEC sequence simultaneously acquires spin echo and multiple stimulated echoes with varying diffusion weighting.
  • The optimal number of stimulated echoes was determined to minimize diffusion coefficient error (D).

Related Experiment Videos

  • In vitro and in vivo experiments were conducted to compare MISSTEC with the conventional spin-echo IVIM method.

    • Main Results:

    • Water-diffusion coefficient (D) values obtained using MISSTEC demonstrated good agreement with those derived from the conventional spin-echo IVIM method.
    • The MISSTEC sequence achieved a total acquisition time that was half of the classic IVIM method.
    • Error in diffusion coefficient measurement was minimized by optimizing the number of stimulated echoes.

    Conclusions:

    • The MISSTEC sequence provides an accurate and significantly faster alternative for measuring water-diffusion coefficients.
    • This method holds potential for improving the efficiency of diffusion MRI studies in both research and clinical settings.