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Endometrial pathology and infertility
V Ruíz-Velasco1, G González Alfani, L Pliego Sánchez
1Universidad Nacional Autónoma de México, Mexico City, Mexico.
Objective:
To call attention to endometrial pathologies, which in addition to causing menstrual problems, are a cause of infertility.
Design:
Controlled clinical study.
Setting:
Specialized unit in the management of infertile patients.
Patient(S):
Fifteen infertile women between the ages of 26 and 39 years and suffering infertility from endometrial problems for a period of 4 to 18 years were included in the study. Six patients had primary infertility and nine others had secondary infertility.
Intervention(S):
Once the endometrial pathology was diagnosed, treatment was initiated according to the type of problem: hysteroscopy, curettage, and hormonal replacement with or without corticoids or antiphymic drugs.
Main Outcome Measure(S):
Clinical studies, laboratory tests, hormonal serum levels, and endoscopy.
Result(S):
After initiating specific treatment for each of the pathologies, menstruation was re-established in 14 of 15 patients. Nine patients became pregnant (8 of 10 cases with bone, squamous cell, or muscular metaplasia).
Conclusion(S):
Pathological changes of the endometrium are causes of infertility. These problems are not as rare as thought. They must be searched for carefully and diagnosed promptly. The majority carry a good prognosis when adequately treated.