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Rhodococcus equi pneumonia

D H Johnson1, B A Cunha

  • 1Infectious Disease Division, Winthrop-University Hospital, Mineola, New York 11501, USA.

Seminars in Respiratory Infections
|March 1, 1997
PubMed
Summary
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Rhodococcus equi, formerly Corynebacterium equi, causes pneumonia in foals and opportunistic infections in immunocompromised individuals. Treatment requires long-term intracellularly active antimicrobials.

Area of Science:

  • Microbiology
  • Veterinary Medicine
  • Infectious Diseases

Background:

  • Corynebacterium equi, now Rhodococcus equi, is a gram-positive rod first isolated in 1923.
  • It is known to cause suppurative bronchopneumonia in foals.
  • Rhodococcus equi is increasingly recognized as a pathogen in immunocompromised humans.

Purpose of the Study:

  • To review the characteristics and clinical manifestations of Rhodococcus equi infections.
  • To highlight the significance of this pathogen in both veterinary and human medicine.
  • To discuss treatment strategies for Rhodococcus equi infections.

Main Methods:

  • Literature review of Rhodococcus equi.
  • Analysis of clinical presentations and epidemiological data.

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  • Summary of treatment approaches.

    • Main Results:

    • Rhodococcus equi infections commonly manifest as cavitary pneumonia, mimicking tuberculosis.
    • Extrapulmonary infections are also observed.
    • Long-term antimicrobial therapy is essential for successful treatment.

    Conclusions:

    • Rhodococcus equi is an important pathogen with diverse clinical presentations.
    • Effective management necessitates prolonged treatment with intracellularly active agents.
    • Awareness of R equi's pathogenicity is crucial, especially in at-risk populations.