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Updated: Sep 21, 2026

A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice
Published on: May 10, 2013
[Rapid determination of creatinine in the blood and urine by 1st-generation Autoanalyzer]
Abstract:
Two procedures for the determination of serum and urinary creatinine by first generation AutoAnalyzer have been positively tested. These methods enable to perform these analyses by cam 60 and 100 respectively, in order to make the influence of carryover neglectable. Very regular peaks with clear-cut resolution can be obtained. The range of concentrations which can be reliably evaluated corresponds to 0,5-10,0 mg/100 ml for serum and to 20-500 mg/100 ml for urine, for this analysis neither diluition nor the dialysis of the sample are required.
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