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[The membrane oxygenator]

A Thomas1

  • 1Institut Pasteur, C.N.R.S. Sorbonne, Hôpital Broussais, Paris.

Bulletin De L'Academie Nationale De Medecine
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

This study introduces a novel membrane oxygenator for extracorporeal circulation, utilizing dissolved oxygen and a phosphate buffer aerosol. It enabled the first adult open-heart surgery with extracorporeal circulation, maintaining normal physiological constants.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Surgery
  • Respiratory Physiology

Context:

  • Development of extracorporeal circulation (ECC) techniques for open-heart surgery.
  • Need for efficient blood oxygenation and carbon dioxide removal during ECC.
  • Challenges in maintaining physiological stability during complex cardiac procedures.

Purpose:

  • To present a new membrane oxygenator design for extracorporeal blood oxygenation.
  • To demonstrate the efficacy of using dissolved oxygen conveyed by a buffer aerosol.
  • To validate the device's performance in adult open-heart surgery.

Summary:

  • A novel membrane oxygenator employs a microporous plastic film rotor with a phosphate buffer aerosol to oxygenate blood.
  • Venous blood is oxygenated via the rotor's external surface, facilitating CO2 release without microbubble formation.

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  • The system maintained normal physiological parameters during high-flow adult open-heart operations and proved membrane stability.

    • Impact:

    • Pioneered the first adult open-heart operation utilizing extracorporeal circulation in France (1958).
    • Successfully supported approximately sixty open-heart surgeries, demonstrating clinical feasibility.
    • Established a foundation for advanced extracorporeal membrane oxygenation (ECMO) technologies.