Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

TiO2-polymer composites for biomedical applications

J Peña1, M Vallet-Regí, J San Román

  • 1Departamento de Química Inorgánica y Bioinorgánica, Facultad de Farmacia, U.C.M., Madrid, Spain.

Journal of Biomedical Materials Research
|April 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Few-cycle self-compression of GW mid-IR pulses in an anti-resonant fiber in ambient air: publisher's note.

Optics letters·2025
Same author

Few-cycle self-compression of GW mid-IR pulses in an anti-resonant fiber in ambient air.

Optics letters·2025
Same author

High-quality pulse compression using a hybrid all-bulk multipass cell scheme.

Optics express·2025
Same author

Reliable change indices for 16 neuropsychological tests at six different time points.

Neurologia·2025
Same author

Long-term brain structural and cognitive outcomes in a low-risk preterm-born sample.

Scientific reports·2024
Same author

Amygdala structure and function and its associations with social-emotional outcomes in a low-risk preterm sample.

Brain structure & function·2024
Same journal

Optimizing the tensile properties of polyvinyl alcohol hydrogel for the construction of a bioprosthetic heart valve stent.

Journal of biomedical materials research·2002
Same journal

Wear of conventional and cross-linked ultra-high-molecular-weight polyethylene acetabular cups against polished and roughened CoCr femoral heads in a biaxial hip simulator.

Journal of biomedical materials research·2002
Same journal

Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its cytocompatibility.

Journal of biomedical materials research·2002
Same journal

Light scattering and in vitro biocompatibility studies of poly (vinyl pyrrolidone) derivatives with amino-acid-dependent groups.

Journal of biomedical materials research·2002
Same journal

Immobilization of an oxalate-degrading enzyme on silicone elastomer.

Journal of biomedical materials research·2002
Same journal

An evaluation of the cytotoxic effects of orthodontic bonding adhesives upon a primary human oral gingival fibroblast culture and a permanent, human oral cancer-cell line.

Journal of biomedical materials research·2002
See all related articles

New composite hydrogels made of poly(acrylic acid) and poly(methyl methacrylate) reinforced with titanium dioxide exhibit pH-sensitive swelling. These advanced biomaterials show tunable hydration properties crucial for various applications.

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Biomaterials Engineering

Background:

  • Hydrogels are versatile materials with applications in drug delivery and tissue engineering.
  • Tuning hydrogel properties like swelling is critical for optimizing performance.
  • Titanium dioxide (TiO2) is a biocompatible ceramic with potential for material reinforcement.

Purpose of the Study:

  • To prepare and characterize composite hydrogels of poly(acrylic acid) (PAA) and poly(methyl methacrylate) (PMMA) reinforced with TiO2.
  • To investigate the swelling behavior of these composite hydrogels in response to different pH conditions.
  • To understand the role of TiO2 and polymer interactions in modulating hydrogel hydration.

Main Methods:

  • Reactive molding was used to synthesize composite hydrogels.

Related Experiment Videos

  • Thermogravimetry, 1H-NMR spectroscopy, and scanning electron microscopy were employed for characterization.
  • Swelling behavior was assessed in buffered solutions at pH 7.0 and 8.0 at 37°C.

    • Main Results:

    • Composite hydrogels with varying TiO2 content and a fixed PAA/PMMA ratio were successfully prepared.
    • The hydrogels demonstrated significant consistency even in hydrated states.
    • Swelling behavior was found to be sensitive to the pH of the surrounding medium.
    • Polar interactions between PAA's carboxylic groups and TiO2 surfaces influenced hydration processes.

    Conclusions:

    • The developed TiO2-reinforced PAA/PMMA composite hydrogels exhibit tunable swelling properties.
    • pH sensitivity is a key characteristic, modulated by specific polymer-ceramic interactions.
    • These findings suggest potential for controlled hydration in biomaterial applications.