Anergic disseminated toxoplasmosis in a patient with AIDS. Case report

In recent years, Toxoplasma gondii has emerged as an important life-threatening opportunistic pathogen in compromised hosts. Toxoplasma gondii is considered the opportunistic agent most frequently causing severe encephalitis in AIDS. Less common manifestations of active toxoplasma infection include extracerebral and disseminated disease. The diagnosis of extraneural or disseminated toxoplasmosis requires a high index of suspicion because the clinical and laboratory manifestations are nonspecific and may be confused with those of other opportunistic diseases. The authors report an unusual case of anergic disseminated toxoplasmosis in AIDS, with a brief comment on the clinical and diagnostic aspects of this rare, dangerous, but treatable complication.