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Enterococcus faecium in hospitals

J J Wade1

  • 1Dulwich Public Health Laboratory & Medical Microbiology, King's College School of Medicine & Dentistry, London, UK.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|February 1, 1997
PubMed
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Enterococcus faecium is a problematic nosocomial pathogen due to its intrinsic and acquired resistance, leading to multi-drug resistance. Understanding its distinct characteristics is crucial for controlling its spread in healthcare settings.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Healthcare Epidemiology

Background:

  • Enterococci are significant nosocomial pathogens.
  • Enterococcus faecium and Enterococcus faecalis are the most common clinical isolates.
  • Early recognition of enterococcal traits is noted.

Purpose of the Study:

  • To highlight the fundamental differences between Enterococcus faecium and Enterococcus faecalis.
  • To explain the mechanisms behind Enterococcus faecium's success as a pathogen.
  • To emphasize the need for clear nomenclature in understanding nosocomial pathogens.

Main Methods:

  • Review of early century literature on enterococcal characteristics.
  • Analysis of antimicrobial resistance mechanisms in Enterococcus faecium.

Related Experiment Videos

  • Comparison of Enterococcus faecium and Enterococcus faecalis.

    • Main Results:

    • Enterococcus faecium exhibits intrinsic antimicrobial resistance, enhanced by acquired mechanisms.
    • This resistance can lead to glycopeptide-multiply-resistant strains.
    • Enterococcus faecium survives in the environment and on hands, facilitating spread.

    Conclusions:

    • Enterococcus faecium is an emerging, problematic nosocomial pathogen.
    • Its resistance profile and environmental survival contribute to its success.
    • Confusing historical nomenclature hinders understanding and control efforts.