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Related Experiment Videos

Equine protozoal myeloencephalitis

R J MacKay1

  • 1Department of Large Animal Clinical Sciences, University of Florida, College of Veterinary Medicine, Gainesville, USA.

The Veterinary Clinics of North America. Equine Practice
|April 1, 1997
PubMed
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Equine protozoal myeloencephalitis (EPM), a common neurologic disease in horses, is caused by Sarcocystis neurona. While treatable, outcomes for EPM in horses can be incomplete, necessitating further research into its life cycle and management.

Area of Science:

  • Veterinary Neurology
  • Parasitology
  • Equine Medicine

Background:

  • Equine protozoal myeloencephalitis (EPM) is a prevalent neurologic condition affecting horses in the Americas.
  • Clinical signs range from gait abnormalities to severe brain disease, often progressing over time.
  • Sarcocystis neurona is the identified causative agent, with serologic evidence suggesting widespread exposure in US horse populations.

Purpose of the Study:

  • To review the current understanding of Sarcocystis neurona's life cycle.
  • To consolidate information on the diagnosis and clinical presentation of EPM.
  • To summarize available treatment strategies and outcomes for equine protozoal myeloencephalitis.

Main Methods:

  • Literature review of scientific articles on EPM and Sarcocystis neurona.

Related Experiment Videos

  • Analysis of diagnostic methods for EPM.
  • Evaluation of treatment efficacy and prognosis for affected horses.

    • Main Results:

    • New insights into the life cycle of Sarcocystis neurona are presented.
    • Common clinical signs, including gait abnormalities and brain disease, are detailed.
    • Treatment for EPM is discussed, noting often incomplete responses to antimicrobial therapies.

    Conclusions:

    • EPM is a significant neurologic disease in horses caused by Sarcocystis neurona.
    • Early diagnosis and appropriate treatment are crucial for managing EPM.
    • Further research into the Sarcocystis neurona life cycle may improve EPM treatment and outcomes.