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Related Experiment Videos

Whither triazolam?

R E Johnson1, B McFarland, G T Woodson

  • 1Center for Health Research, Kaiser Permanente Northwest Division, Portland, OR 97227, USA.

Medical Care
|April 1, 1997
PubMed
Summary

Removing triazolam from a health maintenance organization (HMO) formulary significantly reduced its use. Elderly individuals were identified as long-term users, with their usage patterns showing less dramatic changes.

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Area of Science:

  • Pharmacology
  • Health Services Research

Background:

  • Triazolam, a short-acting benzodiazepine, was widely prescribed.
  • Health maintenance organizations (HMOs) manage drug formularies to influence prescribing patterns.

Purpose of the Study:

  • To evaluate the impact of removing triazolam from an HMO's formulary on its prescribing and usage.
  • To analyze changes in triazolam user demographics and usage duration post-formulary deletion.

Main Methods:

  • Retrospective analysis of benzodiazepine dispensings for HMO members over a 5-year period (1989-1993).
  • Comparison of triazolam user numbers, demographics, total exposure, and daily doses before and after formulary deletion.

Main Results:

  • Triazolam dispensing decreased tenfold by 1993 compared to 1989.
  • Elderly patients were identified as frequent long-term users with the most extended exposure.
  • Changes in user demographics and usage patterns were less pronounced than the overall decrease in use.

Conclusions:

  • Formulary management, even with an open and advisory approach, can significantly alter provider prescribing behavior.
  • The study highlights the impact of formulary decisions on medication use within an HMO setting.

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