Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stability in cognitive dysfunctions in schizophrenic patients

B R Rund1, N I Landrø, A L Orbeck

  • 1Institute of Psychology, University of Oslo, Norway.

Psychiatry Research
|March 24, 1997
PubMed
Summary

This study classified cognitive dysfunctions in schizophrenia using a trait/state model. Some deficits are linked to illness state, while others may reflect enduring traits or vulnerability factors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thalamic nuclei volumes across psychiatric and neurological disorders: a multi-site magnetic resonance imaging study.

Translational psychiatry·2026
Same author

Executive deficits after SARS-CoV-2 infection: A cross-sectional population study.

Brain, behavior, & immunity - health·2024
Same author

Neurocognitive effects of an omega-3 fatty acid and vitamins E+C in schizophrenia: A randomised controlled trial.

Prostaglandins, leukotrienes, and essential fatty acids·2017
Same author

Cognitive rehabilitation in multiple sclerosis: a randomized controlled trial.

Acta neurologica Scandinavica·2015
Same author

Reward responsiveness in patients with chronic pain.

European journal of pain (London, England)·2015
Same author

Serotonin transporter polymorphisms predict response inhibition in healthy volunteers.

Neuroscience letters·2014

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Schizophrenia is characterized by cognitive dysfunctions.
  • Understanding whether these deficits are state-dependent or trait-dependent is crucial for treatment.

Purpose of the Study:

  • To classify cognitive dysfunctions in schizophrenia using a trait/state model.
  • To differentiate between episode-linked and trait-dependent cognitive deficits.

Main Methods:

  • Examined 15 schizophrenic patients and 14 controls on 10 cognitive measures.
  • Assessed patients during acute psychotic and partial remission states.
  • Utilized backward masking and memory tests.

Main Results:

  • Six cognitive measures showed deficits in schizophrenic patients.

Related Experiment Videos

  • Four measures (backward masking, long-term memory) appeared trait-dependent.
  • One short-term memory measure was episode-linked.
  • Other deficits were vulnerability factors, prominent in acute states but persisting in remission.

    • Conclusions:

    • Cognitive dysfunctions in schizophrenia have both state-dependent and trait-dependent components.
    • Vulnerability factors contribute to persistent cognitive deficits.
    • The trait/state model provides a framework for understanding schizophrenia's cognitive profile.