Multiple sclerosis or multiphasic disseminated encephalomyelitis? A new question about an old problem. Case report

A 42 year-old woman developed paraplegia that resolved in six months, followed by sudden right hemiparesis and dysphasia two years later. The clinical work-up, including CT and MR scans, visual evoked potential, CSF examination and cerebral biopsy suggested the possibility of either multiple sclerosis or multiphasic disseminated encephalomyelitis. The differential diagnosis between both conditions is discussed.