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Tourette syndrome. Secondary tic disorders
1Morton and Gloria Shulman Movement Disorders Centre, Division of Neurology, Department of Medicine, the Toronto Hospital, University of Toronto, Toronto, Ontario, Canada.
Neurologic Clinics
|May 1, 1997
Summary
This review examines neurologic and neuropsychiatric disorders linked to tics. Understanding secondary tic disorders may illuminate basal ganglia function and Tourette syndrome development.
Area of Science:
- Neurology
- Neuropsychiatry
- Movement Disorders
Background:
- Tics are associated with various neurologic and neuropsychiatric conditions.
- Certain medications influencing neurotransmitter systems can worsen tics.
Purpose of the Study:
- To review the relationship between tics and other disorders.
- To explore the impact of medications on tic exacerbation.
- To enhance understanding of basal ganglia physiology and Tourette syndrome pathogenesis.
Main Methods:
- Literature review of studies on tics, associated disorders, and drug effects.
- Analysis of the role of neurotransmitter systems in tic modulation.
- Synthesis of findings to explore secondary tic disorder mechanisms.
Main Results:
- Multiple neurologic and neuropsychiatric disorders are linked to tic development.
- Pharmacological agents affecting neurotransmitter systems can precipitate or worsen tics.
- Secondary tic disorders offer insights into basal ganglia dysfunction.
Conclusions:
- Investigating secondary tic disorders is crucial for understanding Tourette syndrome.
- Basal ganglia physiology is central to tic pathogenesis.
- Further research into drug-induced tics can inform therapeutic strategies.