Oronasal distribution of ventilation at different ages

The route of breathing, oral or nasal, is a determinant of the doses of inhaled pollutants delivered to target sites in the upper and lower respiratory tracts. We measured partitioning of ventilation, using a divided oronasal mask during a submaximal exercise test, in 37 male and female subjects who ranged in age from 7 to 72 y. The following four patterns of breathing were evident during exercise: (1) nasal only (13.5%), nasal shifting to oronasal (40.5%), oronasal only (40.5%), and oral only (5.4%). Children (i.e., 7-16 y of age) displayed more variability than adults with respect to their patterns of ventilation with exercise. Young adults (i.e., 17-30 y of age) who initially breathed nasally with exercise switched to oral ventilation at a lower percentage of the previously measured maximum ventilation (10.8%) than older subjects (31.8%). The partitioning of ventilation between the nasal and oral routes follows complex patterns that cannot be predicted readily by the age, gender, or nasal airway resistance of the subject.