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Updated: Aug 12, 2026
08:12
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
[Is there an age limit for cadaveric kidney donors currently?]
F Cofán Pujol1, F Oppenheimer Salinas, R Talbot-Wright
1Unidad de Transplante Renal, Universidad de Barcelona, España.
Archivos Espanoles De Urologia
|December 1, 1996
Summary
Kidney transplants from donors aged 60-70 show satisfactory graft survival with careful selection, despite increased acute tubular necrosis. Grafts from donors over 70 are generally not recommended due to poor outcomes.
Area of Science:
- Nephrology
- Transplantation immunology
- Geriatric medicine
Context:
- Increasing demand for kidney transplants necessitates utilizing older donor grafts.
- Age-related changes in donor kidneys raise concerns about graft function and survival.
- Cyclosporine era has impacted the use of older donor kidneys.
Purpose:
- Analyze age-related kidney changes.
- Review clinical outcomes of older donor kidney transplants.
- Discuss ethical considerations for using elderly donor grafts.
Summary:
- Kidney grafts from donors aged 60-70 demonstrate comparable short-to-medium term survival to younger donors, with higher rates of acute tubular necrosis.
- Long-term data on grafts from donors over 65 is limited.
- Grafts from donors over 70 have yielded unsatisfactory results in our experience.
Impact:
- Establishes selection criteria for utilizing kidney grafts from donors aged 60-70.
- Highlights the need for further research into long-term outcomes and alternative immunosuppression for older donor kidney transplants.
- Informs clinical decisions regarding the use of elderly donor kidneys in transplantation.
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01:28Kidney Transplant I: Introduction
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