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Reduction of oxazepam to desmethyldiazepam by human intestinal bacteria
T Okamura1, W Sugiura, M Miyazawa
1Osaka Perfectural Institute of Public Health, Japan.
Biological & Pharmaceutical Bulletin
|April 1, 1996
Abstract:
The biotransformation of oxazepam by Bifidobacterium bifidum was studied. The major metabolite was purified by chromatographic methods and found to be desmethyldiazepam using NMR, IR and other physicochemical data.
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