Related Experiment Videos
Correlation between serum creatine kinase activities and anorexia in cats
A J Fascetti1, G E Mauldin, G N Mauldin
1Elmer and Mamdouha Bobst Hospital, Animal Medical Center, New York, NY 10021, USA.
Journal of Veterinary Internal Medicine
|January 1, 1997
Summary
Serum creatine kinase (CK) activity is elevated in anorectic cats, indicating malnutrition. Monitoring CK levels can help assess nutritional support effectiveness in feline patients.
Area of Science:
- Veterinary Medicine
- Biochemistry
- Animal Nutrition
Background:
- Lack of reliable biochemical markers for identifying feline malnutrition.
- Human studies suggest elevated creatine kinase (CK) in malnutrition, decreasing with nutritional intervention.
Purpose of the Study:
- To evaluate serum CK activity in anorectic cats.
- To assess the utility of serum CK for monitoring nutritional support in cats.
Main Methods:
- Serum CK activity was measured in healthy cats (n=25) and anorectic cats receiving nutritional support (n=25).
- Comparison of CK levels between groups and over time during nutritional support.
- Correlation analysis with aspartate transaminase (AST) and lactate dehydrogenase (LDH).
Main Results:
- Anorectic cats exhibited significantly higher serum CK activity compared to controls (P < .001).
- Positive correlations were found between CK and AST (r=.59, P<.05) and LDH (r=.41, P<.05).
- Serum CK levels decreased significantly within 48 hours of nutritional support and normalized with continued feeding.
Conclusions:
- Serum CK activity is a potential biomarker for assessing malnutrition in cats.
- Monitoring serum CK levels can be useful for evaluating the efficacy of nutritional support in anorectic cats.