Related Experiment Video
Updated: Aug 16, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
[Promotion Program Health Survey (SGO). IX. Evaluation of the program section 'Toxicology']
1Adviesgroep Stimuleringsprogramma Gezondheidsonderzoek (SGO), Den Haag.
Abstract:
As a part of the SGO Health Research Promotion Programme, in collaboration with the Toxicological Research Stimulation Programme, a research programme in the field of toxicology was realized. The study ran from 1990 to 1994 (4 years) and comprised animal and clinical research into the possible adverse effects of exposure of the foetus and the neonate to polychlorobiphenyls (PCBs), polychlorodibenzoparadioxins and polychlorodibenzofurans via the placenta and maternal milk. The clinical studies in neonates revealed a slight alteration of the thyroid metabolism (still within normal limits) after increased exposure to dioxides and PCB (as measured in maternal plasma, cord plasma and maternal milk), while slight neurological abnormalities without clinical relevance were also observed. It is concluded from these study results that there are no grounds to advise against breast feeding.
Related Concept Videos
Drug Regulation
Sampling Plans
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...
Therapeutic Drug Monitoring: Drug Analysis Methods
Toxicity Testing in Animals

