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[Normal values for spirometry lung function values and peak flow for 7-18-year-old probands]
H Luttmann1, R Kaaden, L Kreienbrock
1Arbeitssicherheit und Umweltmedizin, Bergische Universität GH Wuppertal.
Pneumologie (Stuttgart, Germany)
|January 1, 1997
Summary
This study developed prediction equations for lung function in children aged 7-18, excluding asthmatics and smokers. The derived equations for respiratory health provide upper-range volume and mid-range flow predictions compared to existing data.
Area of Science:
- Environmental Health
- Pulmonology
- Pediatric Health
Context:
- Prospective cohort study conducted in Southwest Germany (1977, 1979, 1985).
- Focused on long-term effects of air pollution on respiratory health.
- Included 6,625 individuals aged 7 to 18 years, excluding asthmatics, smokers, and extremely overweight individuals.
Purpose:
- To derive prediction equations for pulmonary function parameters.
- To analyze the functional relationship between pulmonary function and anthropometric measures.
- To establish reference values for lung function in healthy children and adolescents.
Summary:
- Analyzed 10,605 spirometric measurements using regression analysis.
- Developed separate regression equations for boys and girls for FVC, FEV0.75, FEV1.0, MMEF, and peak-flow.
- Used logarithmic transformations of standing height, weight, and age as predictors.
Impact:
- Prediction values for lung volume parameters are at the upper end of existing reference data.
- Prediction values for lung flow parameters are in the middle range of existing reference data.
- Provides updated reference equations for assessing pediatric pulmonary function.