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[Krükenberg tumors of breast origin. 10 cases]
G Le Bouëdec1, M de Latour, O Levrel
1Centre Régional de Lutte Contre le Cancer, Jean Perrin, Clermont-Ferrand.
Objective:
To assess the characteristic features of ovarian carcinoma mucocellular secondary to breast cancer.
Methods:
A retrospective pathology evaluation of ovariectomy specimens was conducted to compare the histological types with the original pathology diagnosis of breast cancer.
Results:
Ten cases of ovarian carcinoma mucocellular were observed. Histologically, the ovarian stroma presented voluminous mucin-containing vacuoles in epitheliomatous cells with peripheralized nuclei. In 7 out of 10 cases, the primary breast cancer was invasive lobular carcinoma.
Discussion:
These pathology findings are in agreement with comparative studies on the metastatic behavior of different histological types of breast cancer: invasive lobular carcinoma differs from invasive ductal carcinoma by its tropism for gastrointestinal and internal genital organs.