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Updated: Sep 17, 2026

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
[Digestive hemorrhage in cirrhosis]
1Service d'hépato-gastro-entérologie CHU, Angers.
Abstract:
Variceal bleeding is the second cause of death in cirrhosis. To achieve haemostasis, sclerotherapy (or banding) is the first line treatment but vasoactive drugs (terlipressin or somatostatin) are an alternative and even a complement. Porto-systemic shunt is to be rapidly considered if a second endoscopic treatment has failed. Primary prevention lies on beta-blockers (propranolol or nadolol). Organic nitrates are an alternative and even a complement. Secondary prevention lies on banding or sclerotherapy; beta-blockers are an alternative and even a complement.
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