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Updated: Aug 16, 2026

Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish
Published on: May 25, 2017
[Cirrhosis in children]
1Hépatologie pédiatrique Hôpital de Bicêtre. Le Kremlin-Bicêtre.
Insights
Identifying the cause of pediatric cirrhosis is vital for treatment. Early liver transplantation offers a high survival rate, emphasizing timely intervention before liver failure occurs.
Area of Science:
- Pediatric Gastroenterology and Hepatology
- Metabolic Disorders
- Immunology
Abstract:
Chronic cholestasis, starting early in life, inborn errors of metabolism and chronic hepatitis are the main causes of cirrhosis in children. Precise identification of the cause is crucial because effective therapy is available for many of them. Close follow-up is necessary for all the child's life to prevent, detect and manage the complications and to decide on liver transplantation when no effective therapy is available. Results of liver transplantation in children with cirrhosis indicate that close to 80% of children will be alive 10 years after surgery. Liver transplantation must be carried out before signs of liver failure are present.
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